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For a comprehensive overview of all TRIUMPH trials and retatrutide's development timeline, see our complete retatrutide guide

In trials in which adult patients were randomized prior to dose-escalation, more patients treated with WEGOVY, compared with placebo, had maximum changes from baseline at any visit of 10 to 19 bpm (41% versus 34%, respectively) and 20 bpm or more (26% versus 16%, respectively)

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They should not be combined because the effects on appetite and digestion would be unpredictable