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The 2021 study revealed that there were more than 4000 articles discussing this concept, demonstrating the significance of this research area 58

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Women and people who are assigned female at birth who have excess weight have a higher incidence of menstrual dysfunction and anovulation

These uric acid crystals activate pattern recognition receptors (PRRs), including Toll-like receptors (TLRs), NOD-like receptors, and the NLRP3 inflammasome