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Ongoing assessment allows for the refinement of dosage to maximize results while ensuring patient safety

Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)

Missed doses: If a dose is missed, skip the missed dose, and take the next dose the following day Take on an empty stomach in the morning with water (up to 4 ounces of water)

Treatment Switching and Long-Term Parameter Progression Following application of the treatment effects in the first year of the analysis, HbA1c was modelled to follow the UKPDS progression equation, and patients were assumed to receive oral semaglutide or comparator treatment until HbA1c exceeded 7.5% (58 mmol/mol), which is the threshold for treatment intensification defined in the NICE guidelines [6]

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